Hiperglucemia inducida por glucocorticoides en el paciente hospitalizado: enfoque y manejo

  • Rossanna Tous Lopera Fundación Universitaria de Ciencias de la Salud
  • Andrés Felipe Coy Barrera Fundación Universitaria de Ciencias de la Salud
  • William Rojas García Fundación Universitaria de Ciencias de la Salud


La hiperglucemia inducida por glucocorticoides es un escenario frecuente al cual se enfrenta el clínico durante su práctica hospitalaria diaria, constituyendo un reto en el abordaje y control del estado metabólico de estos pacientes, con el fin de disminuir su morbimortalidad asociada. Presentamos el caso clínico de una paciente de género femenino de 69 años con antecedente de diabetes mellitus tipo 2 y linfoma no Hodgkin, hospitalizada para inicio de ciclo quimioterapéutico, durante el cual se documentan hiperglucemias sostenidas de difícil manejo. La paciente recibió tratamiento con esquema basalbolo y un bolo adicional de insulina NPH titulado según las dosis y tipo de glucocorticoide aplicado, alcanzando adecuado control metabólico.

Se realiza una revisión de la literatura respecto a la hiperglucemia inducida por glucocorticoides, su abordaje y tratamiento, y las recomendaciones existentes en cuanto al uso de insulina NPH como esquema adicional correctivo.



Biografía del autor


Fellow Endocrinología Fundación Universitaria de Ciencias de la Salud.


Fellow Endocrinología Fundación Universitaria de Ciencias de la Salud


Profesor Titular Fundación Universitaria de Ciencias de la Salud, Jefe de Servicio Endocrinología Hospital San José


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Diabetes Technol Ther 2014; 16: 874-879.
TOUS LOPERA, Rossanna; COY BARRERA, Andrés Felipe; ROJAS GARCÍA, William. Hiperglucemia inducida por glucocorticoides en el paciente hospitalizado: enfoque y manejo. Revista Colombiana de Endocrinología, Diabetes & Metabolismo, [S.l.], v. 6, n. 1, p. 55-61, mar. 2019. ISSN 2389-9786. Disponible en: <http://revistaendocrino.org/index.php/rcedm/article/view/469>. Fecha de acceso: 22 abr. 2019
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