@article{Fletcher_Trejos A._Adams_Barreto_2018, title={Efecto de 8 años de Yodificación de la sal sobre la endemia bociogena en Panamá (1969 - 1971)}, volume={-12}, url={https://revistaendocrino.org/index.php/rcedm/article/view/178}, DOI={10.53853/encr.-12.1.178}, abstractNote={<p><span style="font-weight: 400;">Hasta ahora la yodificacion de la</span><span style="font-weight: 400;"> </span><span style="font-weight: 400;">sal es el método  mas seguro  para  la profilaxis del  bocio </span><span style="font-weight: 400;">e</span><span style="font-weight: 400;">ndémico, </span><span style="font-weight: 400;">y en </span><span style="font-weight: 400;">grandes sectores </span><span style="font-weight: 400;">de la población</span><span style="font-weight: 400;"> del </span><span style="font-weight: 400;">mundo </span><span style="font-weight: 400;">se han obte­</span><span style="font-weight: 400;">nido  resultados  </span><span style="font-weight: 400;">favorables</span><span style="font-weight: 400;">. </span><span style="font-weight: 400;">Este método </span><span style="font-weight: 400;">se </span><span style="font-weight: 400;">inició </span><span style="font-weight: 400;">en </span><span style="font-weight: 400;">Panama en 1968, y a</span><span style="font-weight: 400;">hora  </span><span style="font-weight: 400;">tra</span><span style="font-weight: 400;">tamos de establecer</span><span style="font-weight: 400;"> el grado  de  prevalencia </span><span style="font-weight: 400;">actual </span><span style="font-weight: 400;">del bocio endemico </span><span style="font-weight: 400;">en </span><span style="font-weight: 400;">una </span><span style="font-weight: 400;">po</span><span style="font-weight: 400;">blacion  piloto</span><span style="font-weight: 400;">.</span></p> <p><span style="font-weight: 400;">En </span><span style="font-weight: 400;">dicha  </span><span style="font-weight: 400;">población l</span><span style="font-weight: 400;">a </span><span style="font-weight: 400;">frecue</span><span style="font-weight: 400;">n</span><span style="font-weight: 400;">cia de  bocio palpable  antes  </span><span style="font-weight: 400;">de l</span><span style="font-weight: 400;">a in</span><span style="font-weight: 400;">i</span><span style="font-weight: 400;">ciación del </span><span style="font-weight: 400;">programa de l</span><span style="font-weight: 400;">a yodización de la sal para  consumo humano era de 94.1%. Al examinar  recientemente a 178 personas </span><span style="font-weight: 400;">(39.5% </span><span style="font-weight: 400;">de l</span><span style="font-weight: 400;">a </span><span style="font-weight: 400;">población actual del pueblo  pi</span><span style="font-weight: 400;">loto), </span><span style="font-weight: 400;">el porcentaje </span><span style="font-weight: 400;">de  bocio  palpable o visible, doble del tamaño normal, ha des</span><span style="font-weight: 400;">cendido a un  </span><span style="font-weight: 400;">2</span><span style="font-weight: 400;">4</span><span style="font-weight: 400;">.7%</span><span style="font-weight: 400;">, y este se</span><span style="font-weight: 400;"> </span><span style="font-weight: 400;">presenta  </span><span style="font-weight: 400;">en </span><span style="font-weight: 400;">pacientes que  pertenecen a la tercera década de la vida en</span><span style="font-weight: 400;"> </span><span style="font-weight: 400;">adelante</span><span style="font-weight: 400;">.</span></p> <p><span style="font-weight: 400;">Los </span><span style="font-weight: 400;">n</span><span style="font-weight: 400;">i</span><span style="font-weight: 400;">veles </span><span style="font-weight: 400;">de T3 y T4 determinados, </span><span style="font-weight: 400;">son </span><span style="font-weight: 400;">sensiblemente iguales a los que nor</span><span style="font-weight: 400;">malmente </span><span style="font-weight: 400;">se eneuentran en l</span><span style="font-weight: 400;">a </span><span style="font-weight: 400;">ci</span><span style="font-weight: 400;">u</span><span style="font-weight: 400;">dad de  Panama. Tres pecientes sinembargo,  presentaron hallazgos</span><span style="font-weight: 400;"> </span><span style="font-weight: 400;">clínicos </span><span style="font-weight: 400;">y de  labora</span><span style="font-weight: 400;">t</span><span style="font-weight: 400;">orio compa</span><span style="font-weight: 400;">t</span><span style="font-weight: 400;">ibles con  hiperfunción  </span><span style="font-weight: 400;">tiroi</span><span style="font-weight: 400;">dea.  </span><span style="font-weight: 400;">Se </span><span style="font-weight: 400;">encontró </span><span style="font-weight: 400;">una  tendencia a la </span><span style="font-weight: 400;">nodul</span><span style="font-weight: 400;">aridad </span><span style="font-weight: 400;">y a l</span><span style="font-weight: 400;">a predomin</span><span style="font-weight: 400;">anc</span><span style="font-weight: 400;">ia </span><span style="font-weight: 400;">del sexo </span><span style="font-weight: 400;">femenino</span><span style="font-weight: 400;">. </span><span style="font-weight: 400;">La ausencia de </span><span style="font-weight: 400;">antic</span><span style="font-weight: 400;">ue</span><span style="font-weight: 400;">r</span><span style="font-weight: 400;">pos microsómicos  </span><span style="font-weight: 400;">t</span><span style="font-weight: 400;">iroideos e i</span><span style="font-weight: 400;">nfiltración </span><span style="font-weight: 400;">li</span><span style="font-weight: 400;">n</span><span style="font-weight: 400;">f</span><span style="font-weight: 400;">o</span><span style="font-weight: 400;">­</span><span style="font-weight: 400;">cita</span><span style="font-weight: 400;">r</span><span style="font-weight: 400;">ia  </span><span style="font-weight: 400;">en </span><span style="font-weight: 400;">las biopsias  quirúrgicas </span><span style="font-weight: 400;">descartan la presencia </span><span style="font-weight: 400;">de  </span><span style="font-weight: 400;">tiroiditis </span><span style="font-weight: 400;">crónica  asociada.</span></p> <p><span style="font-weight: 400;"><strong> </strong></span></p> <p><strong>SUMMARY</strong></p> <p><strong>Effect of eight years of salt  Iodination on endemic goiter in Panama  (1969-1977)</strong></p> <p><span style="font-weight: 400;">Currently, </span><span style="font-weight: 400;">salt  iodination </span><span style="font-weight: 400;">is the  </span><span style="font-weight: 400;">safest   method  </span><span style="font-weight: 400;">used </span><span style="font-weight: 400;">for  </span><span style="font-weight: 400;">prophyla</span><span style="font-weight: 400;">x</span><span style="font-weight: 400;">is of endemic </span><span style="font-weight: 400;">goiter; </span><span style="font-weight: 400;">favourable </span><span style="font-weight: 400;">resu</span><span style="font-weight: 400;">lts </span><span style="font-weight: 400;">have </span><span style="font-weight: 400;">been </span><span style="font-weight: 400;">obtained in </span><span style="font-weight: 400;">la</span><span style="font-weight: 400;">rge sections of </span><span style="font-weight: 400;">world  population.</span></p> <p><span style="font-weight: 400;">This  method  was begun in Panama </span><span style="font-weight: 400;">in 1968; now, </span><span style="font-weight: 400;">we tried  to establish the  degree of </span><span style="font-weight: 400;">current prevalence of </span><span style="font-weight: 400;">endemic goiter in a pilot </span><span style="font-weight: 400;">town.</span></p> <p><span style="font-weight: 400;">In such  </span><span style="font-weight: 400;">town, frequency </span><span style="font-weight: 400;">of  palpable goiter </span><span style="font-weight: 400;">i</span><span style="font-weight: 400;">n </span><span style="font-weight: 400;">1968 was of  </span><span style="font-weight: 400;">94.</span><span style="font-weight: 400;">1<em>% </em></span><span style="font-weight: 400;">A recent </span><span style="font-weight: 400;">survey  </span><span style="font-weight: 400;">carried </span><span style="font-weight: 400;">out  </span><span style="font-weight: 400;">in 178  patients </span><span style="font-weight: 400;">(39,5%, of the </span><span style="font-weight: 400;">population) </span><span style="font-weight: 400;">showed  </span><span style="font-weight: 400;">that  </span><span style="font-weight: 400;">the percentage </span><span style="font-weight: 400;">of  </span><span style="font-weight: 400;">palpable </span><span style="font-weight: 400;">or  visible goiter, tw</span><span style="font-weight: 400;">ice  </span><span style="font-weight: 400;">normal size, had </span><span style="font-weight: 400;">fallen  to 24,7% present in</span><span style="font-weight: 400;"> </span><span style="font-weight: 400;">patients belonging  to third decade of life or olde</span><span style="font-weight: 400;">r</span><span style="font-weight: 400;">.</span></p> <p><span style="font-weight: 400;">T3 </span><span style="font-weight: 400;">and </span><span style="font-weight: 400;">T4 </span><span style="font-weight: 400;">levels are similar to the  normals found  in </span><span style="font-weight: 400;">the </span><span style="font-weight: 400;">city of  Panama.Three </span><span style="font-weight: 400;">subjects had clinical and </span><span style="font-weight: 400;">laboratory evidence of hyperthyroidism</span><span style="font-weight: 400;">.  A trend  to node </span>formation  and   predominance  in  females was found.  Abscence of  microsomal antibodies and  lymphocytic  infiltration in surgical specimens rules  out a concomitant chronic thyroiditis.</p>}, number={1}, journal={Revista Colombiana de Endocrinología, Diabetes & Metabolismo}, author={Fletcher, Pablo E. and Trejos A., José and Adams, Josefina and Barreto, Marco}, year={2018}, month={Jan.}, pages={21–27} }