TY - JOUR AU - Fletcher, Pablo E. AU - Trejos A., José AU - Adams, Josefina AU - Barreto, Marco PY - 2018/01/10 Y2 - 2024/03/28 TI - Efecto de 8 años de Yodificación de la sal sobre la endemia bociogena en Panamá (1969 - 1971) JF - Revista Colombiana de Endocrinología, Diabetes & Metabolismo JA - Rev.ACE VL - -12 IS - 1 SE - Original Articles DO - 10.53853/encr.-12.1.178 UR - https://revistaendocrino.org/index.php/rcedm/article/view/178 SP - 21-27 AB - <p><span style="font-weight: 400;">Hasta ahora la&nbsp;yodificacion de la</span><span style="font-weight: 400;">&nbsp;</span><span style="font-weight: 400;">sal es el método &nbsp;mas seguro &nbsp;para&nbsp; la profilaxis del &nbsp;bocio </span><span style="font-weight: 400;">e</span><span style="font-weight: 400;">ndémico,&nbsp;</span><span style="font-weight: 400;">y en </span><span style="font-weight: 400;">grandes sectores </span><span style="font-weight: 400;">de&nbsp;la población</span><span style="font-weight: 400;">&nbsp;del </span><span style="font-weight: 400;">mundo </span><span style="font-weight: 400;">se han obte­</span><span style="font-weight: 400;">nido &nbsp;resultados &nbsp;</span><span style="font-weight: 400;">favorables</span><span style="font-weight: 400;">. </span><span style="font-weight: 400;">Este método&nbsp;</span><span style="font-weight: 400;">se </span><span style="font-weight: 400;">inició&nbsp;</span><span style="font-weight: 400;">en </span><span style="font-weight: 400;">Panama en 1968, y a</span><span style="font-weight: 400;">hora &nbsp;</span><span style="font-weight: 400;">tra</span><span style="font-weight: 400;">tamos de establecer</span><span style="font-weight: 400;">&nbsp;el grado &nbsp;de &nbsp;prevalencia&nbsp;</span><span style="font-weight: 400;">actual </span><span style="font-weight: 400;">del bocio endemico </span><span style="font-weight: 400;">en </span><span style="font-weight: 400;">una </span><span style="font-weight: 400;">po</span><span style="font-weight: 400;">blacion &nbsp;piloto</span><span style="font-weight: 400;">.</span></p><p><span style="font-weight: 400;">En </span><span style="font-weight: 400;">dicha &nbsp;</span><span style="font-weight: 400;">población l</span><span style="font-weight: 400;">a </span><span style="font-weight: 400;">frecue</span><span style="font-weight: 400;">n</span><span style="font-weight: 400;">cia de &nbsp;bocio palpable &nbsp;antes &nbsp;</span><span style="font-weight: 400;">de l</span><span style="font-weight: 400;">a in</span><span style="font-weight: 400;">i</span><span style="font-weight: 400;">ciación del </span><span style="font-weight: 400;">programa de l</span><span style="font-weight: 400;">a yodización de la sal para &nbsp;consumo humano era de 94.1%. Al examinar &nbsp;recientemente a 178 personas&nbsp;</span><span style="font-weight: 400;">(39.5%&nbsp;</span><span style="font-weight: 400;">de l</span><span style="font-weight: 400;">a </span><span style="font-weight: 400;">población actual del pueblo &nbsp;pi</span><span style="font-weight: 400;">loto), </span><span style="font-weight: 400;">el porcentaje </span><span style="font-weight: 400;">de &nbsp;bocio &nbsp;palpable o visible, doble del tamaño normal, ha des</span><span style="font-weight: 400;">cendido a un &nbsp;</span><span style="font-weight: 400;">2</span><span style="font-weight: 400;">4</span><span style="font-weight: 400;">.7%</span><span style="font-weight: 400;">, y este se</span><span style="font-weight: 400;">&nbsp;</span><span style="font-weight: 400;">presenta &nbsp;</span><span style="font-weight: 400;">en </span><span style="font-weight: 400;">pacientes que &nbsp;pertenecen a la tercera década de la vida en</span><span style="font-weight: 400;">&nbsp;</span><span style="font-weight: 400;">adelante</span><span style="font-weight: 400;">.</span></p><p><span style="font-weight: 400;">Los </span><span style="font-weight: 400;">n</span><span style="font-weight: 400;">i</span><span style="font-weight: 400;">veles </span><span style="font-weight: 400;">de T3 y T4 determinados, </span><span style="font-weight: 400;">son </span><span style="font-weight: 400;">sensiblemente iguales a los que nor</span><span style="font-weight: 400;">malmente </span><span style="font-weight: 400;">se eneuentran en l</span><span style="font-weight: 400;">a </span><span style="font-weight: 400;">ci</span><span style="font-weight: 400;">u</span><span style="font-weight: 400;">dad de &nbsp;Panama. Tres pecientes sinembargo,&nbsp;&nbsp;presentaron hallazgos</span><span style="font-weight: 400;">&nbsp;</span><span style="font-weight: 400;">clínicos </span><span style="font-weight: 400;">y de &nbsp;labora</span><span style="font-weight: 400;">t</span><span style="font-weight: 400;">orio compa</span><span style="font-weight: 400;">t</span><span style="font-weight: 400;">ibles con &nbsp;hiperfunción &nbsp;</span><span style="font-weight: 400;">tiroi</span><span style="font-weight: 400;">dea. &nbsp;</span><span style="font-weight: 400;">Se&nbsp;</span><span style="font-weight: 400;">encontró&nbsp;</span><span style="font-weight: 400;">una &nbsp;tendencia a la&nbsp;</span><span style="font-weight: 400;">nodul</span><span style="font-weight: 400;">aridad </span><span style="font-weight: 400;">y a l</span><span style="font-weight: 400;">a predomin</span><span style="font-weight: 400;">anc</span><span style="font-weight: 400;">ia&nbsp;</span><span style="font-weight: 400;">del sexo </span><span style="font-weight: 400;">femenino</span><span style="font-weight: 400;">. </span><span style="font-weight: 400;">La ausencia de </span><span style="font-weight: 400;">antic</span><span style="font-weight: 400;">ue</span><span style="font-weight: 400;">r</span><span style="font-weight: 400;">pos microsómicos &nbsp;</span><span style="font-weight: 400;">t</span><span style="font-weight: 400;">iroideos e i</span><span style="font-weight: 400;">nfiltración </span><span style="font-weight: 400;">li</span><span style="font-weight: 400;">n</span><span style="font-weight: 400;">f</span><span style="font-weight: 400;">o</span><span style="font-weight: 400;">­</span><span style="font-weight: 400;">cita</span><span style="font-weight: 400;">r</span><span style="font-weight: 400;">ia &nbsp;</span><span style="font-weight: 400;">en </span><span style="font-weight: 400;">las biopsias &nbsp;quirúrgicas&nbsp;</span><span style="font-weight: 400;">descartan la presencia </span><span style="font-weight: 400;">de &nbsp;</span><span style="font-weight: 400;">tiroiditis </span><span style="font-weight: 400;">crónica &nbsp;asociada.</span></p><p><span style="font-weight: 400;"><strong>&nbsp;</strong></span></p><p><strong>SUMMARY</strong></p><p><strong>Effect of eight years of salt &nbsp;Iodination on endemic goiter in Panama &nbsp;(1969-1977)</strong></p><p><span style="font-weight: 400;">Currently, </span><span style="font-weight: 400;">salt &nbsp;iodination </span><span style="font-weight: 400;">is the &nbsp;</span><span style="font-weight: 400;">safest &nbsp;&nbsp;method &nbsp;</span><span style="font-weight: 400;">used </span><span style="font-weight: 400;">for &nbsp;</span><span style="font-weight: 400;">prophyla</span><span style="font-weight: 400;">x</span><span style="font-weight: 400;">is of endemic&nbsp;</span><span style="font-weight: 400;">goiter;&nbsp;</span><span style="font-weight: 400;">favourable </span><span style="font-weight: 400;">resu</span><span style="font-weight: 400;">lts </span><span style="font-weight: 400;">have&nbsp;</span><span style="font-weight: 400;">been </span><span style="font-weight: 400;">obtained in </span><span style="font-weight: 400;">la</span><span style="font-weight: 400;">rge sections of </span><span style="font-weight: 400;">world &nbsp;population.</span></p><p><span style="font-weight: 400;">This &nbsp;method &nbsp;was begun in Panama </span><span style="font-weight: 400;">in 1968; now, </span><span style="font-weight: 400;">we tried &nbsp;to establish the &nbsp;degree of </span><span style="font-weight: 400;">current prevalence of </span><span style="font-weight: 400;">endemic goiter in a pilot </span><span style="font-weight: 400;">town.</span></p><p><span style="font-weight: 400;">In such &nbsp;</span><span style="font-weight: 400;">town, frequency </span><span style="font-weight: 400;">of &nbsp;palpable&nbsp;goiter&nbsp;</span><span style="font-weight: 400;">i</span><span style="font-weight: 400;">n </span><span style="font-weight: 400;">1968 was of &nbsp;</span><span style="font-weight: 400;">94.</span><span style="font-weight: 400;">1<em>%&nbsp;</em></span><span style="font-weight: 400;">A recent&nbsp;</span><span style="font-weight: 400;">survey &nbsp;</span><span style="font-weight: 400;">carried </span><span style="font-weight: 400;">out &nbsp;</span><span style="font-weight: 400;">in 178&nbsp; patients </span><span style="font-weight: 400;">(39,5%, of the </span><span style="font-weight: 400;">population) </span><span style="font-weight: 400;">showed &nbsp;</span><span style="font-weight: 400;">that &nbsp;</span><span style="font-weight: 400;">the percentage&nbsp;</span><span style="font-weight: 400;">of &nbsp;</span><span style="font-weight: 400;">palpable </span><span style="font-weight: 400;">or &nbsp;visible goiter, tw</span><span style="font-weight: 400;">ice &nbsp;</span><span style="font-weight: 400;">normal size,&nbsp;had </span><span style="font-weight: 400;">fallen &nbsp;to 24,7% present in</span><span style="font-weight: 400;">&nbsp;</span><span style="font-weight: 400;">patients belonging &nbsp;to third decade of life or olde</span><span style="font-weight: 400;">r</span><span style="font-weight: 400;">.</span></p><p><span style="font-weight: 400;">T3 </span><span style="font-weight: 400;">and </span><span style="font-weight: 400;">T4 </span><span style="font-weight: 400;">levels are similar to the &nbsp;normals found &nbsp;in </span><span style="font-weight: 400;">the </span><span style="font-weight: 400;">city of &nbsp;Panama.Three&nbsp;</span><span style="font-weight: 400;">subjects had clinical and </span><span style="font-weight: 400;">laboratory&nbsp;evidence of hyperthyroidism</span><span style="font-weight: 400;">.&nbsp; A trend &nbsp;to node </span>formation &nbsp;and &nbsp;&nbsp;predominance &nbsp;in &nbsp;females was&nbsp;found.&nbsp; Abscence of&nbsp; microsomal antibodies and &nbsp;lymphocytic &nbsp;infiltration in surgical specimens rules &nbsp;out a concomitant chronic thyroiditis.</p> ER -