Effectiveness of IDegLira in Type-2 Diabetes Patients During the COVID-19 Pandemic: A Teleconsultation Follow-up
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Keywords

Insulin degludec
IDegLira
liraglutide
type-2 diabetes

How to Cite

Parra Serrano, G. A., Torres Langhammer, M. P., Pinto Arias, A. J., & Serrano-Gómez, S. (2022). Effectiveness of IDegLira in Type-2 Diabetes Patients During the COVID-19 Pandemic: A Teleconsultation Follow-up. Revista Colombiana De Endocrinología, Diabetes &Amp; Metabolismo, 9(4). https://doi.org/10.53853/encr.9.4.740

Abstract

Introduction: The current management of type 2 diabetes mellitus (T2D) requires a comprehensive approach to achieve goals, emphasizing treatment compliance through periodic surveillance.

Purpose: The purpose of this study was to determine the effectiveness of insulin degludec/liraglutide therapy (IDegLira) on glycemic control in adults with T2D in a real-world setting, with follow-up care provided via teleconsultation during the COVID-19 pandemic.

Materials and methods: Analysis of a real-world anonymized database of patients with T2D, treated in a specialized medical institution between March 2020 and March 2021. HbA1c levels and fasting blood glucose were evaluated at three and six months of follow-up.

Results: We included 61 patients between the age of 43 and 94 years. Most of the patients used oral antidiabetics (75.41%), 85.25% had insulin formulations (basal or basal-bolus), and half of the subjects (55.74%) had insulin-combined formulations. From an average level of HbA1c at baseline of 8.44% (SD 1.4), significant reductions were observed at three months (-0.48%, CI -0.10 to -0.86) and six months-(0.94%, CI -0.55 to -1.33), consistent with a decrease in fasting glycemia (-37.80 mg/dL, CI -21.62 to -53.97 at six months) and with an increase in the proportion of patients achieving glycemic goals. Insulin requirements (total daily dose) decreased on average 11.3 U (CI -6.59 to -16.01, p 0.00). No episodes of significant hypoglycemia were reported.

Conclusions: In the real world, IDegLira generated significant changes towards glycemic control in adults with T2D, with no reports of hypoglycemia for up to 6 months in the context of virtual medical care.

https://doi.org/10.53853/encr.9.4.740
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Copyright (c) 2022 Revista Colombiana de Endocrinología, Diabetes & Metabolismo

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