Glycaemic variability by stepwise glycaemic self-monitoring in subjects with type 2 diabetes
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Glycemic Control
Diabetes Mellitus, Type 2
Blood Glucose Self-Monitoring
Health Education

How to Cite

Pérez Guadrón , C. E. ., Frías Ordoñez, J. S., Bravo Bernal , N. ., Pacheco Pacheco , A. F. ., Manrique Chaparro, N. J. ., & Cabra Cadena, J. D. . (2023). Glycaemic variability by stepwise glycaemic self-monitoring in subjects with type 2 diabetes. Revista Colombiana De Endocrinología, Diabetes &Amp; Metabolismo, 10(2).


Background: In type 2 diabetes beyond the state of chronic hyperglycemia, other indices of dysglycemia such as glycemic variability and recurrent episodes of hypoglycemia have been found to contribute to adverse outcomes.

Purpose: to compare glycometry under a stepped glycemic self-monitoring modality in patients with type 2 diabetes, in order to identify a prognostic factor to optimize glycemic control, based on the analysis of glycemic variability.

Methodology: case series, with a study sample of glycometric data of stepped self-monitoring in three subjects, during 5 years, with an average of 3,400 observed data. A multivariate linear model and post-hoc multiple comparisons tests were used. Glycemic variability was evaluated using mean blood glucose, standard deviation and coefficient of variation for each meal time.

Results: The total number of samples analyzed had a coefficient of variation lower than 36%. The three individuals presented different trends throughout the study period. The data collected leaned towards hypoglycemia. There were no significant differences in the 6 meal times.

Conclusions: In current practice the goal is to decrease glycemic variability, with low risk of hypoglycemia. Self-monitoring of blood glucose is useful to reduce the risk of hypoglycemia and improve glycemic control.
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