Keywords
Hypothyroidism
Prevalence
Renal Insufficiency
Chronic
Thyrotropin
How to Cite
Abstract
Background: In chronic kidney disease (CKD) the presence of various endocrine disorders has been seen, hypothyroidism being one of them, and has a strong impact on its evolution. Its incidence in our country is little known in this group of patients.
Purpose: To establish the prevalence of hypothyroidism in patients with a recent diagnosis of non-dialytic chronic kidney disease (NDCKD), and to analyze whether demographic, clinical, and laboratory variables make it possible to differentiate them from euthyroid patients with NDCKD.
Methodology: Patients consulted during a period of 5 years, at the nephrology service of the Hospital de Caldas and Universidad de Caldas due to deterioration in renal function, including only those who met criteria compatible with CKD. Demographic, clinical, and laboratory variables were evaluated in all of them as part of a nephroprotection program. Hypothyroidism was diagnosed if the TSH value was greater than 4.5 mIU/L.
Results: In a population of 1,332 patients consulted, of whom 535 met the inclusion criteria, hypothyroidism occurred in 29.2% of patients with CKD. 25.23% with TSH values between 4.5 and 10, and 3.74% for values greater than 10 mUI/L. We did not find demographic, clinical or laboratory variables that would allow us to differentiate between euthyroid and hypothyroid patients with CKD.
Conclusions: There are no parameters that lead to suspect the presence of Hypothyroidism in patients with NDCKD. We recommend that upon admission to the nephroprotection program, and due to its importance, TSH and FT4 be routinely performed on everyone.
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