Endocrine diseases in infants and adolescents and the exposure to endocrine disruptors
Cover of our Vol. 11, Issue 2, 2024
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Keywords

Endocrine Disruptors
Diseases of the Endocrine System
Pediatrics
Child
Adolescent
Environmental Pollutants

How to Cite

Briceño Rodríguez, L. L. ., Céspedes Salazar, C. ., & Forero Ronderos, C. . (2024). Endocrine diseases in infants and adolescents and the exposure to endocrine disruptors . Revista Colombiana De Endocrinología, Diabetes &Amp; Metabolismo, 11(2). https://doi.org/10.53853/encr.11.2.872

Abstract

Background: The influence of contact with endocrine disruptors, both in the prenatal and postnatal periods, has generated concern due to its possible relationship with the development of endocrinological diseases in the pediatric population.

Purpose: Compile scientific evidence regarding the presentation of endocrinological diseases in children and adolescents as a consequence of exposure to endocrine disruptors.

Methodology: In this narrative review, we examine the literature published on this topic using electronic databases and handsearching of specialized journals. A total of 33 articles were selected.

Results: A relationship was found between contact with these substances and the development of non-communicable diseases, such as obesity, diabetes, metabolic syndrome, growth and development disorders, and alterations in thyroid function. It has also been shown that exposure to these compounds can have long-term impacts on endocrine and reproductive development.

Conclusions: Additional research needs to be conducted to address gaps in current knowledge and establish a robust scientific basis to support public health decision-making.

https://doi.org/10.53853/encr.11.2.872
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References

Gorini F, Bustaffa E, Coi A, Iervasi G, Bianchi F. Bisphenols as environmental triggers of thyroid dysfunction: clues and evidence. Int J Environ Res Public Health. 2020;17(8):2654. https://doi.org/10.3390/ijerph17082654

Stukenborg JB, Mitchell RT, Söder O. Endocrine disruptors and the male reproductive system. Best Pract Res Clin Endocrinol Metab. 2021;35(5):101567 https://doi.org/10.1016/j.beem.2021.101567

Kabir ER, Rahman MS, Rahman I. A review on endocrine disruptors and their possible impacts on human health. Environ Toxicol Pharmacol. 2015;40(1):241-58 https://doi.org/10.1016/j.etap.2015.06.009

La Merrill MA, Vandenberg LN, Smith MT, Goodson W, Browne P, Patisaul HB, et al. Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. Nat Rev Endocrinol. 2020;16(1):45-57. https://doi.org/10.1038/s41574-019-0273-8

Anne B, Raphael R. Endocrine Disruptor Chemicals. En: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, et al., editores. Endotext [Internet]. South Dartmouth, Massachusetts, Estados Unidos: MDText.com, Inc.; 2000 [actualizado 2021 mzo. 16; citado 2023 may]. https://www.ncbi.nlm.nih.gov/books/NBK569327/

Diamanti-Kandarakis E, Bourguignon JP, Giudice LC, Hauser R, Prins GS, Soto AM, et al. Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocr Rev. 2009;30(4):293-342. https://doi.org/10.1210/er.2009-0002

The Endocrine Disruption Exchange. Comprendiendo la disrupcio?n endocrina [Internet]. Colorado, Estados Unidos: TEDX; 2023 [citado 2023 my. 23]. https://endocrinedisruption.org/assets/media/documents/EDC%20Fact%20Sheet-Spanish%20Translation%2020180131.pdf

Predieri B, Iughetti L, Bernasconi S, Street ME. Endocrine disrupting chemicals’ effects in children: what we know and what we need to learn? Int J Mol Sci. 2022;23(19):11899. https://doi.org/10.3390/ijms231911899

Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR, Lee DH, et al. Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev. 2012;33(3):378-455. https://doi.org/10.1210/er.2011-1050

Kiess W, Häussler G, Vogel M. Endocrine-disrupting chemicals and child health. Vol. 35, Best Pract Res Clin Endoc Metab. 2021;35(5):101516. https://doi.org/10.1016/j.beem.2021.101516

Gore AC, Chappell VA, Fenton SE, Flaws JA, Nadal A, Prins GS, et al. EDC-2: The Endocrine Society’s second scientific statement on endocrine-disrupting chemicals. Endocr Rev. 2015;36(6):E1-150. https://doi.org/10.1210/er.2015-1010

Perng W, Cantoral A, Soria-Contreras DC, Betanzos-Robledo L, Kordas K, Liu Y, et al. Exposición a químicos disruptores endócrinos obesogénicos y obesidad en niños y jóvenes de origen latino o hispano en Estados Unidos y Latinoamérica: una perspectiva del curso de la vida. Obes Rev. 2021;22(supl. 5):e13352. https://doi.org/10.1111/obr.13352

Pozo Román J, Márquez Rivera M, Muñoz Calvo MT. Pubertad precoz y retraso puberal. Adolescere. 2017;5(1):23-49. https://www.adolescenciasema.org/ficheros/REVISTA%20ADOLESCERE/vol5num1-2017/23-49%20Pubertad%20precoz%20y%20retraso%20puberal.pdf

De Angelis M, Schramm KW. Perinatal effects of persistent organic pollutants on thyroid hormone concentration in placenta and breastmilk. Mol Aspects Med. 2022;87:100988. https://doi.org/10.1016/j.mam.2021.100988

Kyriacou A, Tziaferi V, Toumba M. Stress, Thyroid dysregulation, and thyroid cancer in children and adolescents: proposed impending mechanisms. Horm Res Paediatr. 2023;96(1):44-53. https://doi.org/10.1159/000524477

Diamanti-Kandarakis E, Papalou O, Kandaraki E. Endocrine-disrupting chemicals and PCOS: A novel contributor in the etiology of the syndrome. En: Diamanti-Kandarakis E, editora. Polycystic ovary syndrome: challenging issues in the modern era of individualized medicine. Países Bajos: Elsevier; 2022. p. 227-44. https://doi.org/10.1016/B978-0-12-823045-9.00015-8

Saccardo Sarni RO, Kochi C, Suano-Souza FI. Childhood obesity: an ecological perspective. J Pediatr. 2022;98(supl. 1):S38-46. https://doi.org/10.1016/j.jped.2021.10.002

Sargis RM, Simmons RA. Environmental neglect: endocrine disruptors as underappreciated but potentially modifiable diabetes risk factors. Diabetologia. 2019;62:1811-22. https://doi.org/10.1007/s00125-019-4940-z

Heras-González L, Espino D, Jimenez-Casquet MJ, Lopez-Moro A, Olea-Serrano F, Mariscal-Arcas M. Influence of BPA exposure, measured in saliva, on childhood weight. Front Endocrinol (Lausanne). 2022;13:1040583. https://doi.org/10.3389/fendo.2022.1040583

Predieri B, Bruzzi P, Bigi E, Ciancia S, Madeo SF, Lucaccioni L, et al. Endocrine disrupting chemicals and type 1 diabetes. Int J Mol Sci. 2020;21(8):2937. https://doi.org/10.3390/ijms21082937

Baldo F, Barbi E, Tornese G. Delayed pubarche. Ital J Pediatr. 2021;47(1):180. https://doi.org/10.1186/s13052-021-01134-0

Cargnelutti F, Di Nisio A, Pallotti F, Spaziani M, Tarsitano MG, Paoli D, et al. Risk factors on testicular function in adolescents. J Endocrinol Invest. 2022;45(9):1625-39. https://doi.org/10.1007/s40618-022-01769-8

Jung MK, Choi HS, Suh J, Kwon A, Chae HW, Lee WJ, et al. The analysis of endocrine disruptors in patients with central precocious puberty. BMC Pediatr. 2019;19(1):323. https://doi.org/10.1186/s12887-019-1703-4

Lopez-Rodriguez D, Franssen D, Heger S, Parent AS. Endocrine-disrupting chemicals and their effects on puberty. Best Pract Res Clin Endocrinol Metab. 2021;35(5):101579. https://doi.org/10.1016/j.beem.2021.101579

Encarnação T, Pais AA, Campos MG, Burrows HD. Endocrine disrupting chemicals: Impact on human health, wildlife and the environment. Sci Prog. 2019;102(1):3-42. https://doi.org/10.1177/0036850419826802

Ramsey JT, Li Y, Arao Y, Naidu A, Coons LA, Diaz A, et al. Lavender products associated with premature thelarche and prepubertal gynecomastia: case reports and endocrine-disrupting chemical activities. J Clin Endocrinol Metab. 2019;104(11):5393-405. https://doi.org/10.1210/jc.2018-01880

Ak?n L, Kendirci M, Narin F, Kurto?lu S, Hatipo?lu N, Elmal? F. Endocrine disruptors and polycystic ovary syndrome: Phthalates. J Clin Res Pediatr Endocrinol. 2020;12(4):393-400. https://doi.org/10.4274/jcrpe.galenos.2020.2020.0037

Luo Y, Nie Y, Tang L, Xu CC, Xu L. The correlation between UDP-glucuronosyltransferase polymorphisms and environmental endocrine disruptors levels in polycystic ovary syndrome patients. Medicine. 2020;99(11):e19444. https://doi.org/10.1097/MD.0000000000019444

Sakali AK, Bargiota A, Fatouros I, Jamurtas A, Macut D, Mastorakos G, et al. Effects on puberty of nutrition-mediated endocrine disruptors employed in agriculture. Nutrients. 2021;13(11):4184. https://doi.org/10.3390/nu13114184

Kumar M, Sarma DK, Shubham S, Kumawat M, Verma V, Prakash A, et al. Environmental endocrine-disrupting chemical exposure: role in non-communicable diseases. Front Public Health. 2020;8:553850. https://doi.org/10.3389/fpubh.2020.553850

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Copyright (c) 2024 Revista Colombiana de Endocrinología, Diabetes & Metabolismo

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