Successful pregnancy with 15-year-old ovulation induction of post-surgical hypopituitarism
PDF (Español (España))
xhtml (Español (España))

Keywords

pregnancy
pituitary tumors
Somatotroph adenoma
hypopituitarism
fertility
infertility
ovulation induction
assisted reproductive techniques

How to Cite

Duran Morales, M. A., García-Arango, M. ., Ramírez- Ramírez, O. A., Ariza-Parra, E. J., Arango-Martínez, A., & García-Ortega, J. A. (2022). Successful pregnancy with 15-year-old ovulation induction of post-surgical hypopituitarism. Revista Colombiana De Endocrinología, Diabetes &Amp; Metabolismo, 8(3). https://doi.org/10.53853/encr.8.3.675

Abstract

We present the case of a patient with amenorrhea secondary to a history of surgery for pituitary macroadenoma, producer of growth hormone with suprasellar extension and to the cavernous sinus. With postsurgical hypopituitarism and desire for fertility, a controlled ovulation induction was performed, obtaining a twin pregnancy without complications.

In view of the scarce information in the literature on fertility treatment in women with hypopituitarism and its poor result in terms of pregnancy and live birth rates, we want to provide the evidence with the first case reported in Colombia.

https://doi.org/10.53853/encr.8.3.675
PDF (Español (España))
xhtml (Español (España))

References

Overton CE, Davis CJ, West C, Davies MC, Conway GS. High risk pregnancies in hypopituitary women. Hum Reprod. 2002;17:1464–1467.

Kim SY. Diagnosis and Treatment of Hypopituitarism. Endocrinol Metab (Seoul). 2015;30(4):443-455. doi:10.3803/EnM.2015.30.4.443

Vila G, Fleseriu M. Fertility and Pregnancy in Women With Hypopituitarism: A Systematic Literature Review. J Clin Endocrinol Metab. 2020 Mar 1;105(3):dgz112.

Du X, Yuan Q, Yao Y, Li Z, Zhang H. Hypopituitarism and successful pregnancy. Int J Clin Exp Med. 2014;7(12):4660-4665. Published 2014 Dec 15.

Gelbaya TA, Potdar N, Jeve YB, Nardo LG. Definition and epidemiology of unexplained infertility. Obstet Gynecol Surv. 2014;69(2):109-115.

Practice Committee of American Society for Reproductive Medicine. Definitions of infertility and recurrent pregnancy loss: a committee opinion. Fertil Steril 2013;99:63.

American College of Obstetricians and Gynecologists. reVitalize. Gynecology data definitions (version 1.0). Washington, DC: American College of Obstetricians and Gynecologists; 2017.

Carson SA, Kallen AN. Diagnosis and Management of Infertility: A Review. JAMA. 2021;326(1):65–76.

Inder WJ, Jang C. Pituitary disease: An update. Aust J Gen Pract. 2021 Jan-Feb;50(1-2):30-35. doi: 10.31128/AJGP-10-20-5688

Fleseriu M, Hashim IA, Karavitaki N, et al. Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2016; 101:3888.

Raverot G, Burman P, McCormack A, Heaney A, Petersenn S, Popovic V, Trouillas J, Dekkers OM; European Society of Endocrinology. Clinical Practice Guidelines for the management of aggressive pituitary tumours and carcinomas. Eur J Endocrinol. 2018 Jan;178(1):G1-G24.

Malik S, Kiran Z, Rashid MO, et al. Hypopituitarism other than sellar and parasellar tumors or traumatic brain injury assessed in a tertiary hospital. Pak J Med Sci. 2019;35(4):1149-1154.

Idris I, Srinivasan R, Simm A, Page RC. Maternal hypothyroidism in early and late gestation: effects on neonatal and obstetric outcome. Clin Endocrinol (Oxf) 2005;63:560–565.

Ovarian Stimulation TEGGO, Bosch E, Broer S, Griesinger G, Grynberg M, et al. ESHRE guideline: ovarian stimulation for IVF/ICSI†. Hum Reprod Open. 2020 May 1;2020(2):hoaa009.

Hall R, Manski-Nankervis J, Goni N, Davies MC, Conway GS. Fertility outcomes in women with hypopituitarism. Clin Endocrinol (Oxf). 2006 Jul;65(1):71-4.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Copyright (c) 2021 Revista Endocrino

Dimensions


PlumX


Downloads

Download data is not yet available.