Abstract
Eruptive xanthomas are abnormal deposits of lipids and foam cells (represented by lipid-laden macrophages) in the skin. They are related to disorders of lipid metabolism and, less frequently, to monoclonal gammopathies. In a percentage of the cases there is no evidence of a subsequent disease appearing these lesions sporadically. We report the case of a 57-year-old male with a prior history of diabetes mellitus and dyslipidemia, with yellowish papulo-nodular lesions disseminated in the body, clinically and histologically compatible with eruptive xanthomas.
References
2. Villalón G, Martín JM, Monteagudo C, Alonso V, Montesinos E, Jordá E. Xantomas eruptivos en el debut de diabetes mellitus. Actas Dermosifiliogr. 2008;99(5):426-7.
3. Goldstein GD. The Koebner response with eruptive xanthomas. J Am Acad Dermatol, 1984:10(6):1064-5.
4. Gámez Pérez L, Reig Macías I, Gutiérrez Paredes E, Monteagudo Castro C, Jordá Cuevas E. Xantomas eruptivos. Causas, diagnóstico y tratamiento. Piel. 2011;26(10):505-7.
5. Sacchi A, Olivares L. Xantomatosis y dislipoproteinemias: Dermatol. Argent, 2013, 19(3): 174-182
6. Brites FD, Gómez Rosso LA, Boero LE, Rivera S. Clasificación y diagnóstico bioquímico de las dislipemias. Síndrome Metabólico y Riesgo Vascular. Buenos Aires; 2012;150-68
7. Laufs U, Parhofer KG. Simplified algorithm to facilitate communication of familial hypercholesterolaemia. Eur Heart J. 2015;36(43):3004-6.
8. Cepeda LL, Ramos-garibay JA, Calderón DP. Xantomas eruptivos como manifestación inicial de diabetes mellitus e hipertrigliceridemia severa. 2010;19:15-8.
9. Miller M, Stone NJ, Ballantyne C, Bittner V, Criqui MH, Ginsberg HN, et al. Triglycerides and cardiovascular disease: A scientific statement from the American Heart Association. Circulation. 2011;123(20):2292-333.
10. Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL, et al. 2016 European Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2016;37(29):2315-81.
Authors must state that they reviewed, validated and approved the manuscript's publication. Moreover, they must sign a model release that should be sent. A copy may be reviewed here