Keywords
hypopituitarism
traumatic brain injury
cognitive dysfunction
growth hormone
adrenal Insufficiency
depression and psychosocial impact
How to Cite
Abstract
Background: Traumatic brain injury (TBI) is a public health problem with severe neurological and cognitive sequelae that may be associated with endocrine pituitary dysfunction. Pituitary dysfunction increase morbidity, mortality and, depending on the affected axis, has variable cognitive and neurobehavioral repercussions that affect the rehabilitation process and the return to social life of the survivors.
Purpose: We carry out a review about relationship between pituitary hormonal alterations and neurocognitive alterations after the head trauma.
Methodology: A search of the literature was carried out using question, ¿which neurocognitive alterations are associated with post-traumatic brain injury and pituitary dysfunction? Using descriptors pituitary, hypopituitarism, traumatic brain injury, cognitive dysfunction, in the PubMed® and Scopus databases, the same question was asked for each of the pituitary axes.
Results: A total of 48 articles were found in these databases, mainly descriptive papers.
Conclusions: Pituitary disorders related to head trauma should be suspected and studied in patients with this history of importance for neurocognitive disorders and pituitary profile. The diagnosis of pituitary dysfunction should always be questioned in patients with TBI and mild and severe neurocognitive disorders.
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