Factors associated with clinically significant weight gain in patients treated with bariatric surgery
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Bariatric Surgery
Body Mass Index
Chronic Disease
Risk Factors
Weight Loss

How to Cite

Henao Carrillo, D. C., Gómez, A. M., Muñoz, O. M. ., Rubio, C., Rodriguez, N., Ursida, V., Forero, A. M., Pinzón, F. ., & Mikler, R. (2023). Factors associated with clinically significant weight gain in patients treated with bariatric surgery. Revista Colombiana De Endocrinología, Diabetes &Amp; Metabolismo, 10(1). https://doi.org/10.53853/encr.10.1.760


Background: Bariatric surgery allows sustainable weight loss, however, between 15-35% of these patients present weight gain, associated with adverse clinical outcomes.

Purpose: to describe the factors associated with weight gain in a cohort of patients managed in an obesity clinic.

Methodology: A case-control study nested in a cohort was conducted. A case was defined as the patient who presented a weight gain of ?10% with respect to the minimum postoperative weight in at least one control between the second and tenth year of follow-up, and control as any patient who did not meet said criteria. Clinical, anthropometric, surgical variables and life habits were evaluated. The association between each of the variables considered as a risk factor was evaluated through a univariate and multivariate analysis.

Results: 154 patients were included. 31 cases and 123 control cases. In the multivariate analysis, the factors associated with weight gain were pre-surgical BMI >40kg/m2 (OR3.02; 95%CI 1.08-8.46, p=0.035), moderate to intense physical activity (OR 6.07; 95%CI 1.23-29.8 ; p=0.026) and anxiety disorder (OR 5.50; 1.71-17.6; p=0.004). Factors such as pre-surgical weight loss (OR 0.84, 95% CI 0.74-0.98; p=0.021) and diet <1200 calories (OR 0.36; 95% CI 0.13-1.00; p=0.050) decreased the risk of regrowth.

Conclusions: 25% of patients present weight gain two to ten years after bariatric surgery. Pre- and post-surgical factors were associated with weight gain, suggesting the importance of long-term multidisciplinary follow-up in patients treated with surgery.

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