Palabras clave
disfunción sexual
deficiencia de prolactina
disfunción eréctil
serotonina
salud del hombre
Cómo citar
Resumen
Contexto: la prolactina es una hormona con múltiples funciones neuroendocrinas, el rol más estudiado es en la función reproductiva, aún no es claro por qué su deficiencia causa disfunción sexual, sin embargo, se ha relacionado con la función gonadal.
Objetivo: presentar la información actual sobre la estructura y aspectos moleculares de la PRL, el papel de la serotonina, y la relación fisiopatológica de la hipoprolactinemia y la disfunción sexual masculina.
Metodología: revisión de la literatura en las bases de datos PubMed, Lilacs, Embase, Scopus, Scielo, Google Académico y literatura gris utilizando vocabulario controlado DE MeSH, DeCS y Emtree.
Resultados: existe poca evidencia acerca de la hipoprolactinemia y disfunción sexual, sin embargo, parecen ser manifestaciones de una alteración serotoninérgica y sus efectos metabólicos, siendo importante conocer los aspectos básicos, fisiopatológicos y clínicos que convierten a esta entidad en una de las causas asociadas a este síndrome.
Conclusiones: la hipoprolactinemia es uno de los factores de menor protagonismo por la escasa información disponible con respecto a su rol en la disfunción sexual, esto motiva a desarrollar investigaciones que profundicen el entendimiento de la enfermedad.
Citas
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