Impact of exercise on glucose in patients with type 1 diabetes who use a hybrid closed-loop system with the use of a temporary objective
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Keywords

Aerobic exercise
resistance exercise
Automated Insulin Delivery
Hybrid Closed loop system
time in range
hypoglycemia

How to Cite

Gómez Medina, A. M., Henao Carrillo, D. C. ., Robledo, S., Buendia, R., Jaramillo, P., & Muñoz , O. M. . (2022). Impact of exercise on glucose in patients with type 1 diabetes who use a hybrid closed-loop system with the use of a temporary objective. Revista Colombiana De Endocrinología, Diabetes &Amp; Metabolismo, 9(3). https://doi.org/10.53853/encr.9.3.721

Abstract

Introduction: The consensus on exercise management for patients with type 1 diabetes (T1D) does not include recommendations for patients using hybrid closed loop (HCL) systems. Objective: to describe the behavior of interstitial glucose during aerobic exercise (AE) and resistance exercise (RE) in patients with T1D users of HCL systems.

Methodology: Observational pilot study. Patients >18 years of age treated with HCL system were included. Baseline demographic data was recorded and moderate intensity AE and RE physical activity sessions were scheduled according to the consensus recommendations. In both sessions, it was indicated to use a temporary goal 60 minutes before and to measure capillary glucose during physical activity (baseline, 15, 30, 45 and 60 minutes). At the end of the exercise sessions, the data was downloaded from the device.

Results: 10 patients were included (80% women, mean age 41.1±11.8 years) with an TIR between 70-180 mg/dl >90%. During EA the mean basal glucose, 15,13,45 and 60 minutes were 147.1±24.1mg/dl, 131.4±15.5mg/dl, 131.4±15.5mg/dl, 107.9±17mg/dl and 101.3±19.5mg/dl, p <0.05, respectively. During the ER no significant changes were observed with respect to basal glucose. 36 hours after physical activity, there were 2.75 level 1 hypoglycemic events, without severe hypoglycemia.

Conclusions: EA lowers glucose levels early and significantly, while ER glucose levels remain stable. The data reported in this study suggest that the use of SCHA following the consensus guidelines and programming the time goal is safe.

https://doi.org/10.53853/encr.9.3.721
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Copyright (c) 2022 Revista Colombiana de Endocrinología, Diabetes & Metabolismo

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