Keywords
Sexual Dysfunction
Prolactin Deficiency
Erectile Dysfunction
Serotonin
Men's Health
How to Cite
Abstract
Background: Prolactin is a hormone with multiple neuroendocrine functions, its most studied role is in reproductive function, it remains unclear why deficiency of this hormone causes sexual dysfunction, however it has been related with gonadal function.
Purpose: Provide current information on the structure and molecular aspects of PRL, the role of serotonin, and the pathophysiological relationship of hypoprolactinemia and male sexual dysfunction.
Methodology: Literature review in PubMed, LILACS, Embase, Scopus and Scielo databases, Google Scholar and gray literature using the MeSH, DeCS and Emtree controlled vocabulary.
Results: There is little evidence about hypoprolactinemia and sexual dysfunction, nonetheless they seem to be manifestations of a serotonergic alteration and its metabolic effects, thus, it is important to know the basic pathophysiological and clinical aspects that make this entity one of the causes associated with this syndrome.
Conclusions: Hypoprolactinemia is one of the factors of less given distinction due to the scarce information available regarding its role in sexual dysfunction, this motivates the development of research to deepen the understanding of the disease.
References
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