Subacute thyroiditis: Literature review and its relationship with Covid-19
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Subacute thyroiditis
Nonsteroidal anti-inflammatory drugs

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Rueda Perea, M. A. ., Flórez Romero, A. ., & Latorre Núñez, Y. . (2023). Subacute thyroiditis: Literature review and its relationship with Covid-19. Revista Colombiana De Endocrinología, Diabetes &Amp; Metabolismo, 10(1).


Introduction: Subacute thyroiditis (SAT) is the most common painful thyroid inflammatory disorder. It is preceded by predominantly viral respiratory infections.

Purpose: Review of the literature in the Pubmed database of SAT regarding the etiology, and its relationship with the SARS-COV-2 virus, the clinical presentation, and a comparison between the different treatment schemes with glucocorticoids.

Case presentation: 29-year-old female, presented mild respiratory infection by COVID-19. Thyroid function tests with suppressed TSH and increased free T4, previously normal. Absence of symptoms of SAT or other thyroid condition. Thyroid ultrasound with evidence of bilateral adenopathies. Scintigraphy with report of "almost absence of scintigraphic representation of the thyroid gland" with technetium trapping index: 1.4 (N: 2-5-4.5).

Discussion and conclusion: Compromise of the thyroid gland as a sequel to acute respiratory infection by COVID-19, manifests from Graves' disease, Hashimoto's thyroiditis, to subacute thyroiditis, this being the most commonly associated disorder. The clinical course of TSA in SARS-COV-2 is painless; latency period between infection and thyroiditis is shorter or even occurs simultaneously. SAT is an inflammatory thyroid disorder, with SARS-COV-2 being a new causal agent, with changes in clinical presentation. The greatest impact of corticosteroids in the management of subacute thyroiditis is in pain control; consider its use after the use of NSAIDs, and in case of possible recurrence of pain, it should be given for 4-6 weeks.
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